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I have been receiving Zometa via IV infusion for about 3 years now - At first three weekly then after about a year, four weekly - I have breast cancer, bone metastasis. If I take the infusion over 15 minutes....during the following day I will begin with severe vomiting and flu symptoms which last for two days and nights after which I'm fine. However, if I have the infusion over 30 minutes - as advised on the internet way back in the early days of my treatments, I have NO side effects whatsoever - no sickness, no aches & pains! I have spoken to other women who have experienced the same - take the infusion slower, drink plenty of water, and you might just find your horrid side-effects disappear!
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Normalization of serum alkaline phosphatase levels (a key marker for bone turnover) at 6 months was also achieved in a significantly greater proportion of patients receiving single-dose zoledronic acid than those receiving the 60-day risedronate regimen (89 % versus 58 %).

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The effects of intravenous zoledronic acid in Chinese women with postmenopausal osteoporosis.

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Zolendronic acid is also used for the reduction to treat or prevent complications of certain cancers under the name Zometa.

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Thanks for all the information vivian, I am saving it all for future use and will be getting your book in the fall.

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Studies do not support any significant benefit for use beyond 6 years of treatment.

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In the absence of poison, and given the nutrients and exercise it needs, your body has remarkable healing powers.

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While density is an indicator of bone metabolism, the main focus of bone health is simply to prevent fractures, and less dense but healthy and renewed bones have better tensile strength than thicker, denser, older bones.

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I'm afraid of the risks involved with taking the drug, but I definitely do not want to go through this again.

Não sou da área médica, mas tenho osteoporose, uso actonel(suspenso por outro profissional) e uma medica me sugeriu o aclasta(bifosfonato) e outro me sugeriu prolia(desonumab).

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My father hadthe Aclasta infusion a week ago today, I have never seen him so ill.

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However, it is still not clear to me what would be the suggested "protocol" regarding a "real" patient that had already been administered Reclast a half a year ago, and i have to extract her two upper molars?

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Changes in bone-turnover markers were compared with the use of an ANCOVA model based on the log ratio of the post-baseline value to the baseline value, with treatment and log baseline values as explanatory variables.

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Subject: testimonialI was diagnosed with osteoporosis a few years ago.

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After reading comments i “Our Bones Community” I had refused to take Fosamax.

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And you also may want to gradually increase the amount of foods that cause you problems.

Australian Adverse Drug Reactions Bullettin, 2000, 19: 14)Come è noto, la cisapride è stata associata a gravi aritmie cardiache e per tale motivo in molti paesi sono stati presi dei provvedimenti.

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